Potential Therapeutic Effect of Barley on Cardiovascular Diseases

Therapeutic Effect of Barley

Authors

  • Madiha Khan Niazi University Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore, Lahore, Pakistan
  • Farooq Hassan Punjab Healthcare Commission (PHC), Lahore, Pakistan
  • Sahar Imran University Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore, Lahore, Pakistan
  • Zainab Saeed University Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore, Lahore, Pakistan
  • Khadija Riaz University Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore, Lahore, Pakistan
  • Zuha Sohail University Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore, Lahore, Pakistan
  • Muhammad Amjed Ismail Faculty of Eastern Medicine, Hamdard University, Karachi, Pakistan

DOI:

https://doi.org/10.54393/df.v3i02.58

Keywords:

Barley, Medicinal, Therapeutic, Cardiovascular Disease

Abstract

Barley is a fantastic food option for those with various illnesses as well as for those who want to lead a healthy lifestyle. This cereal is a great source of soluble dietary fiber, particularly beta glucans, and it also includes vital vitamins and minerals. For its excellent antioxidant activity and as a source of vitamins and minerals, green barley is advised. Depending on phytonutrients such as -glucan, phenolics, flavonoid, lignans, tocols, sitosterol, and folic, regular consumption of whole wheat grain and its hydroethanolic extracts decreases the risk of chronic ailments (hyperglycemia, malignancy, overweight, cardiac disease. Barley and its products in a recent year had gain an importance due to its counteractive components which play potent role against cardiovascular diseases by lowering down the oxidative stress and improving High density lipoprotein further Lowering down low-density lipoprotein, VLDL ratios further regulating insulin levels and lowering down the spike in blood glucose levels showing potent anti-oxidative and cardiovascular functions. Due to their abundance in these nutrients, barley is effective in promoting healthy bodily function. To enjoy all of the advantages of barley, barley grain is a wonderful option.

References

Guglielmo M, Lin A, Dey D, Baggiano A, Fusini L, Muscogiuri G, et al. Epicardial fat and coronary artery disease: role of cardiac imaging. Atherosclerosis. 2021 Mar; 321: 30-8. doi: 10.1016/j.atherosclerosis.2021.02.008.

Csige I, Ujvárosy D, Szabó Z, Lőrincz I, Paragh G, Harangi M, et al. The impact of obesity on the cardiovascular system. Journal of diabetes research. 2018 Nov; 2018: 1-12. doi: 10.1155/2018/3407306.

Nangia R, Singh H, Kaur K. Prevalence of cardiovascular disease (CVD) risk factors. Medical Journal Armed Forces India. 2016 Oct; 72(4): 315-319. doi: 10.1016/j.mjafi.2014.07.007.

Sidhu GS, Ward C, Ferdinand KC. Racial disparity in atherosclerotic cardiovascular disease in hospitalized patients with diabetes 2005–2015: Potential warning signs for future US public health. American Journal of Preventive Cardiology. 2020 Dec; 4: 100095. doi: 10.1016/j.ajpc.2020.100095.

Jabeur I, Martins N, Barros L, Calhelha RC, Vaz J, Achour L, et al. Contribution of the phenolic composition to the antioxidant, anti-inflammatory and antitumor potential of Equisetum giganteum L. and Tilia platyphyllos Scop. Food and Function. 2017 Jan; 8(3): 975-984. doi: 10.1039/C6FO01778A.

Woldemichael MD. Importance, biology, epidemiology, and management of Loose Smut (Ustilago nuda) of barley (Hordeum vulgare): A Review. East African Journal of Sciences. 2019 Jan; 13(1): 89-108.

Wang Y, Ren X, Sun D, Sun G. Origin of worldwide cultivated barley revealed by NAM-1 gene and grain protein content. Frontiers in Plant Science. 2015 Sep; 6(3): 1-12. doi: 10.3389/fpls.2015.00803.

Punia S, Siroha AK, Sandhu KS, Kaur M. Rheological behavior of wheat starch and barley resistant starch (type IV) blends and their starch noodles making potential. International journal of Biological Macromolecules. 2019 Jun; 130(34): 595-604. doi: 10.1016/j.ijbiomac.2019.03.009.

Zhang J, Xiao X, Dong Y, Shi L, Xu T, Wu F. The anti-obesity effect of fermented barley extracts with Lactobacillus plantarum dy-1 and Saccharomyces cerevisiae in diet-induced obese rats. Food and Function. 2017 Jan; 8(3): 1132-43. doi: 10.1039/C6FO01350C.

Guo H, Lin S, Lu M, Gong JD, Wang LU, Zhang Q, et al. Characterization, in vitro binding properties, and inhibitory activity on pancreatic lipase of β-glucans from different Qingke (Tibetan hulless barley) cultivars. International journal of Biological Macromolecules. 2018 Dec; 120(33): 2517-2522. doi: 10.1016/j.ijbiomac.2018.09.023.

Fritsche S, Wang X, Jung C. Recent advances in our understanding of tocopherol biosynthesis in plants: an overview of key genes, functions, and breeding of vitamin E improved crops. Antioxidants. 2017 Dec; 6(4): 99-121. doi: 10.3390/antiox6040099.

Liao Z, Cai H, Xu Z, Wang J, Qiu C, Xie J, et al. Protective role of antioxidant huskless barley extracts on TNF-α-induced endothelial dysfunction in human vascular endothelial cells. Oxidative Medicine and Cellular Longevity. 2018 May; 15(2): 1-12. doi: 10.1155/2018/3846029.

Gangopadhyay N, Rai DK, Brunton NP, Gallagher E, Hossain MB. Antioxidant-guided isolation and mass spectrometric identification of the major polyphenols in barley (Hordeum vulgare) grain. Food Chemistry. 2016 Nov; 210(33): 212-220. doi: 10.1016/j.foodchem.2016.04.098.

Ma Y, Wang P, Wang M, Sun M, Gu Z, Yang R. GABA mediates phenolic compounds accumulation and the antioxidant system enhancement in germinated huskless barley under NaCl stress. Food Chemistry. 2019 Jan; 270(39): 593-601. doi: 10.1021/jf802846x.

Zhu F. Anthocyanins in cereals: Composition and health effects. Food Research International. 2018 Jul; 109(31): 232-249. doi: 10.1016/j.foodres.2018.04.015.

Casieri V, Matteucci M, Cavallini C, Torti M, Torelli M, Lionetti V. Long-term intake of pasta containing barley (1–3) beta-D-glucan increases neovascularization-mediated cardioprotection through endothelial upregulation of vascular endothelial growth factor and parkin. Scientific Reports. 2017 Oct; 7(1): 1-6. doi: 10.1038/s41598-017-13949-1.

Tong LT, Zhong K, Liu L, Zhou X, Qiu J, Zhou S. Effects of dietary hull-less barley β-glucan on the cholesterol metabolism of hypercholesterolemic hamsters. Food Chemistry. 2015 Feb; 169(23): 344-349. doi: 10.1016/j.foodchem.2014.07.157.

Martínez M, Motilva MJ, de Las Hazas MC, Romero MP, Vaculova K, Ludwig IA. Phytochemical composition and β-glucan content of barley genotypes from two different geographic origins for human health food production. Food Chemistry. 2018 Apr; 245: 61-70. doi: 10.1016/j.foodchem.2017.09.026.

Zhang H, Zhang N, Xiong Z, Wang G, Xia Y, Lai P, et al. Structural characterization and rheological properties of β-D-glucan from hull-less barley (Hordeum vulgare L. var. nudum Hook. f.). Phytochemistry. 2018 Nov; 155(67): 155-163. doi: 10.1016/j.phytochem.2018.08.004.

Sima P, Vannucci L, Vetvicka V. β-glucans and cholesterol. International journal of molecular medicine. 2018 Apr; 41(4): 1799-808. doi: 10.3892/ijmm.2018.3411.

Downloads

Published

2022-12-31
CITATION
DOI: 10.54393/df.v3i02.58
Published: 2022-12-31

How to Cite

Niazi, M. K., Hassan, F. ., Imran, S. ., Saeed, Z. ., Riaz, K. ., Sohail, Z. ., & Amjed Ismail, M. . (2022). Potential Therapeutic Effect of Barley on Cardiovascular Diseases: Therapeutic Effect of Barley . DIET FACTOR (Journal of Nutritional and Food Sciences), 3(02), 03–06. https://doi.org/10.54393/df.v3i02.58

Issue

Section

Review Article

Plaudit

Most read articles by the same author(s)