Phytochemicals And Nutraceuticals as A Promising Drug Candidate in Autism  Spectrum Disorder: Phytochemicals and Nutraceuticals

Maria Aslam; Muhammad  Barkaat Azam

doi:10.54393/df.v3i1.12

Authors

Maria Aslam The University of Lahore
Muhammad Barkaat Azam University Institute of Diet and Nutritional Sciences UIDNS, The University of Lahore UOL, Lahore, Pakistan.

DOI:

https://doi.org/10.54393/df.v3i1.12

Keywords:

Autism, neurological disorders, children, stress, neurodevelopmental disorders

Abstract

Autism is a wide range of neurological illnesses with an unknown etiology that are solely diagnosed based on behavioral testing. The prevalence and frequency of autism spectrum disorder (ASD) have increased during the past twenty years. This condition has been linked to increased oxidative stress and decreased antioxidant capacity. Furthermore, oxidative stress vulnerability in autism may increase due to genetic and environmental factors. ASD develops this disorder in terms of both clinical symptoms and pathological process due to elevated oxidative stress. Changes in complex human behaviors, such as social interaction, communication, and stereotypes, are features of autism. Additionally, autistic children may not be able to handle anxiety and behave inappropriately even in the presence of stimuli that are generally benign. Growing data suggests that epigenetic pathways contribute to the etiology of autism. Many research have tried to find epigenetic biomarkers for ASD up till now. Children with autism spectrum disorder (ASD) typically exhibit pronounced behavioral challenges coupled with social connection problems.

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