Management of Obesity through Diet and Exercise

Management of Obesity


  • Komal Jamil Department of Physical Therapy, Bahria University, Karachi, Pakistan
  • Syeda Rida Baqir Department of Physical Therapy, Bahria University, Karachi, Pakistan
  • Muhammad Faisal Fahim Department of Physical Therapy, Bahria University, Karachi, Pakistan
  • Prem Lata Department of Physical Therapy, Bahria University, Karachi, Pakistan
  • Bismah Khan Department of Physical Therapy, Metropolis Health Centre, Karachi, Pakistan
  • Muneeba Aziz Department of Physical Therapy, Isra University, Karachi, Pakistan



Obesity, Nutrition, Physical Activity, Exercise, Caloric Requirements


Worldwide, Pakistan is ranked as the 6th most highly populated country. Approximately 1.6 million deaths are due to the health problems associated with obesity. Obesity is the root cause of any health problem and can lead to many serious diseases of the heart, lungs, and kidneys, and can cause death. Lack of physical activity, excessive consumption of food, and unawareness is the main cause of obesity in Pakistan. The obesity ratio of people living in urban areas is more than people living in rural. To describe the different types of exercises and diet plans for losing weight in an obese person. This literature review is written by the collection of many search websites like Google Scholar, Pub Med, Sci-Hub, Centre of Disease Control, etc. It is used to enhance the awareness of weight management interventions with the help of evidence-based practice. Weight reduction can be accomplished by following the standard guidelines and different ways of weight management programs.  


Chooi YC, Ding C, Magkos F. The epidemiology of obesity. Metabolism. 2019 Mar; 92: 6-10. doi: 10.1016/j.metabol.2018.09.005. DOI:

GBD 2015 Obesity Collaborators. Health effects of overweight and obesity in 195 countries over 25 years. New England Journal of Medicine. 2017 Jul; 377(1): 13-27. doi: 10.1056/NEJMoa1614362. DOI:

Grassi G, Biffi A, Seravalle G, Trevano FQ, Dell’Oro R, Corrao G, et al. Sympathetic neural overdrive in the obese and overweight state: meta-analysis of published studies. Hypertension. 2019 Aug; 74(2): 349-58. doi: 10.1161/HYPERTENSIONAHA.119.12885. DOI:

Rochira A, Tedesco D, Ubiali A, Fantini MP, Gori D. School gardening activities aimed at obesity prevention improve body mass index and waist circumference parameters in school-aged children: A systematic review and meta-analysis. Childhood Obesity. 2020 Apr; 16(3): 154-73. doi: 10.1089/chi.2019.0253. DOI:

Nam GE, Kim YH, Han K, Jung JH, Park YG, Lee KW, et al. Obesity fact sheet in Korea, 2018: data focusing on waist circumference and obesity-related comorbidities. Journal of Obesity & Metabolic Syndrome. 2019 Dec; 28(4): 236-45. doi: 10.7570/jomes.2019.28.4.236. DOI:

López-Olmedo N, Popkin BM, Mendez MA, Taillie LS. The association of overall diet quality with BMI and waist circumference by education level in Mexican men and women. Public Health Nutrition. 2019 Oct; 22(15): 2777-92. doi: 10.1017/S136898001900065X. DOI:

Petermann-Rocha F, Ulloa N, Martínez-Sanguinetti MA, Leiva AM, Martorell M, Villagrán M, et al. ELHOC-Chile Research Consortium. Is waist-to-height ratio a better predictor of hypertension and type 2 diabetes than body mass index and waist circumference in the Chilean population? Nutrition. 2020 Nov; 79: 110932. doi: 10.1016/j.nut.2020.110932. DOI:

Caneiro JP, Bunzli S, O'Sullivan P. Beliefs about the body and pain: the critical role in musculoskeletal pain management. Brazilian Journal of Physical Therapy. 2021 Jan; 25(1): 17-29. doi: 10.1016/j.bjpt.2020.06.003. DOI:

World Health Organization. WHO European regional obesity report 2022. 2022. [Last cited: 19th Oct 2023]. Available at:

Tanveer M, Hohmann A, Roy N, Zeba A, Tanveer U, Siener M. The Current Prevalence of Underweight, Overweight, and Obesity Associated with Demographic Factors among Pakistan School-Aged Children and Adolescents—An Empirical Cross-Sectional Study. International Journal of Environmental Research and Public Health. 2022 Sep; 19(18): 11619. doi: 10.3390/ijerph191811619. DOI:

Loos RJ and Yeo GS. The Genetics of obesity: from discovery to biology. Nature Reviews Genetics. 2022 Feb; 23(2): 120-33. doi: 10.1038/s41576-021-00414-z. DOI:

Alonso‐Pedrero L, Bes‐Rastrollo M, Marti A. Effects of antidepressant and antipsychotic use on weight gain: a systematic review. Obesity Reviews. 2019 Dec; 20(12): 1680-90. doi: 10.1111/obr.12934. DOI:

San-Cristobal R, Navas-Carretero S, Martínez-González MÁ, Ordovas JM, Martínez JA. Contribution of macronutrients to obesity: implications for precision nutrition. Nature Reviews Endocrinology. 2020 Jun; 16(6): 305-20. doi: 10.1038/s41574-020-0346-8. DOI:

van der Valk ES, van den Akker EL, Savas M, Kleinendorst L, Visser JA, Van Haelst Mm, et al. A comprehensive diagnostic approach to detect underlying causes of obesity in adults. Obesity Reviews. 2019 Jun; 20(6): 795-804. doi: 10.1111/obr.12836. DOI:

Wardelmann K, Blümel S, Rath M, Alfine E, Chudoba C, Schell M, et al. Insulin action in the brain regulates mitochondrial stress responses and reduces diet-induced weight gain. Molecular Metabolism. 2019 Mar; 21: 68-81. doi: 10.1016/j.molmet.2019.01.001. DOI:

Garett R and Young SD. The role of misinformation and stigma in opioid use disorder treatment uptake. Substance Use & Misuse. 2022 Jun; 57(8): 1332-6. doi: 10.1080/10826084.2022.2079133. DOI:

Alwan A, McColl K, Al-Jawaldeh A. Proposed policy priorities for preventing obesity and diabetes in the Eastern Mediterranean Region. World Health Organization; 2017. [Last cited: 19th Oct 2023]. Available at:

Semlitsch T, Stigler FL, Jeitler K, Horvath K, Siebenhofer A. Management of overweight and obesity in primary care—A systematic overview of international evidence‐based guidelines. Obesity Reviews. 2019 Sep; 20(9): 1218-30. doi: 10.1111/obr.12889. DOI:

Wrzosek M, Zawadzka Z, Sawicka A, Bobrowska-Korczak B, Białek A. Impact of fatty acids on obesity-associated diseases and radical weight reduction. Obesity Surgery. 2022 Feb: 2022: 1-3.

Ruban A, Stoenchev K, Ashrafian H, Teare J. Current treatments for obesity. Clinical Medicine. 2019 May; 19(3): 205-12. doi: 10.7861/clinmedicine.19-3-205. DOI:

Pilitsi E, Farr OM, Polyzos SA, Perakakis N, Nolen-Doerr E, Papathanasiou AE, et al. Pharmacotherapy of Obesity: available medications and drugs under investigation. Metabolism. 2019 Mar; 92: 170-92. doi: 10.1016/j.metabol.2018.10.010. DOI:

Altaf A and Abbas MM. Public perception of bariatric surgery. Saudi Medical Journal. 2019; 40(4): 378-83. doi: 10.15537/smj.2019.4.24050. DOI:

Calcaterra V, Cena H, Pelizzo G, Porri D, Regalbuto C, Vinci F, et al. Bariatric surgery in adolescents: To do or not to do? Children. 2021 May; 8(6): 453. doi: 10.3390/children8060453. DOI:

Sivanand A, Gulliver WP, Josan CK, Alhusayen R, Fleming PJ. Weight loss and dietary interventions for hidradenitis suppurativa: a systematic review. Journal of Cutaneous Medicine and Surgery. 2020 Jan; 24(1): 64-72. doi: 10.1177/1203475419874412. DOI:

Semlitsch T, Krenn C, Jeitler K, Berghold A, Horvath K, Siebenhofer A. Long‐term effects of weight‐reducing diets in people with hypertension. Cochrane Database of Systematic Reviews. 2021; 2: CD008274. doi: 10.1002/14651858.CD008274.pub4. DOI:

Moriconi E, Camajani E, Fabbri A, Lenzi A, Caprio M. Very-low-calorie ketogenic diet as a safe and valuable tool for long-term glycemic management in patients with obesity and type 2 diabetes. Nutrients. 2021 Feb; 13(3): 758-72. doi: 10.3390/nu13030758. DOI:

Vargas G, Azarbal J, Tota-Maharaj R. A comparative review of established diets for prevention of cardiovascular disease and newer dietary strategies. Current Problems in Cardiology. 2021 Mar; 46(3): 100582. doi: 10.1016/j.cpcardiol.2020.100582. DOI:

Kelly T, Unwin D, Finucane F. Low-Carbohydrate diets in the management of obesity and type 2 diabetes: a review from clinicians using the approach in practice. International Journal of Environmental Research and Public Health. 2020 Apr; 17(7): 2557. doi: 10.3390/ijerph17072557. DOI:

Bruci A, Tuccinardi D, Tozzi R, Balena A, Santucci S, Frontani R, et al. Very low-calorie ketogenic diet: A safe and effective tool for weight loss in patients with obesity and mild kidney failure. Nutrients. 2020 Jan 27; 12(2): 333. doi: 10.3390/nu12020333. DOI:

Castellana M, Conte E, Cignarelli A, Perrini S, Giustina A, Giovanella L, et al. Efficacy and safety of very low calorie ketogenic diet (VLCKD) in patients with overweight and obesity: A systematic review and meta-analysis. Reviews in Endocrine and Metabolic Disorders. 2020 Mar; 21(1): 5-16. doi: 10.1007/s11154-019-09514-y. DOI:

Gepner Y, Shelef I, Komy O, Cohen N, Schwarzfuchs D, Bril N, et al. The beneficial effects of Mediterranean diet over low-fat diet may be mediated by decreasing hepatic fat content. Journal of Hepatology. 2019 Aug; 71(2): 379-88. doi: 10.1016/j.jhep.2019.04.013. DOI:

Hall KD, Guo J, Courville AB, Boring J, Brychta R, Chen KY, et al. Effect of a plant-based, low-fat diet versus an animal-based, ketogenic diet on ad libitum energy intake. Nature medicine. 2021 Feb; 27(2): 344-53. doi: 10.1038/s41591-020-01209-1. DOI:

Younossi ZM, Corey KE, Lim JK. AGA clinical practice update on lifestyle modification using diet and exercise to achieve weight loss in the management of nonalcoholic fatty liver disease: expert review. Gastroenterology. 2021 Feb; 160(3): 912-8. doi: 10.1053/j.gastro.2020.11.051. DOI:

Mohammadi S and Khademi Ashkezari M. Investigating the benefits of a nutrition training course for weight loss, increasing nutritional awareness, changing food consumption concerns, and increasing motivation for healthy living. Medical Journal of Mashhad University of Medical Sciences. 2020 Apr; 63(1): 2238-45.

Becker A, Gaballa D, Roslin M, Gianos E, Kane J. Novel nutritional and dietary approaches to weight loss for the prevention of cardiovascular disease: ketogenic diet, intermittent fasting, and bariatric surgery. Current Cardiology Reports. 2021 Jul; 23(7): 85. doi: 10.1007/s11886-021-01515-1. DOI:

Freire R. Scientific evidence of diets for weight loss: Different macronutrient composition, intermittent fasting, and popular diets. Nutrition. 2020 Jan; 69: 110549. doi: 10.1016/j.nut.2019.07.001. DOI:

Lundgren JR, Janus C, Jensen SB, Juhl CR, Olsen LM, Christensen RM, et al. Healthy weight loss maintenance with exercise, liraglutide, or both combined. New England Journal of Medicine. 2021 May; 384(18): 1719-30. doi: 10.1056/NEJMoa2028198. DOI:

Wadden TA, Tronieri JS, Butryn ML. Lifestyle modification approaches for the treatment of obesity in adults. American Psychologist. 2020 Feb; 75(2): 235-51. doi: 10.1037/amp0000517. DOI:

Garber CE. The health benefits of exercise in overweight and obese patients. Current Sports Medicine Reports. 2019 Aug; 18(8): 287-91. doi: 10.1249/JSR.0000000000000619. DOI:

Pazzianotto-Forti EM, Moreno MA, Plater E, Baruki SB, Rasera-Junior I, Reid WD. Impact of physical training programs on physical fitness in people with class II and III obesity: A systematic review and meta-analysis. Physical Therapy. 2020 Jun; 100(6): 963-78. doi: 10.1093/ptj/pzaa045. DOI:

Rubino D, Abrahamsson N, Davies M, Hesse D, Greenway FL, Jensen C, et al. Effect of continued weekly subcutaneous semaglutide vs placebo on weight loss maintenance in adults with overweight or obesity: the STEP 4 randomized clinical trial. JAMA. 2021 Apr; 325(14): 1414-25.

Lowe DA, Wu N, Rohdin-Bibby L, Moore AH, Kelly N, Liu YE, et al. Effects of time-restricted eating on weight loss and other metabolic parameters in women and men with overweight and obesity: the TREAT randomized clinical trial. JAMA Internal Medicine. 2020 Nov; 180(11): 1491-9. doi: 10.1001/jamainternmed.2020.4153. DOI:

Johnson NA, Sultana RN, Brown WJ, Bauman AE, Gill T. Physical activity in the management of obesity in adults: A position statement from Exercise and Sport Science Australia. Journal of Science and Medicine in Sport. 2021 Dec; 24(12): 1245-54. doi: 10.1016/j.jsams.2021.07.009. DOI:

Fico BG, Alkatan M, Tanaka H. No changes in appetite-related hormones following swimming and cycling exercise interventions in adults with obesity. International Journal of Exercise Science. 2020; 13(2): 1819-25.

DiMilia PR, Mittman AC, Batsis JA. Benefit-to-risk balance of weight loss interventions in older adults with obesity. Current diabetes reports. 2019 Nov; 19: 1-2. doi: 10.1007/s11892-019-1249-8. DOI:

Herzog W. Reflections on obesity, exercise, and musculoskeletal health. Journal of Sport and Health Science. 2020 Mar; 9(2): 108-9. doi: 10.1016/j.jshs.2019.11.004. DOI:

Asghar A, Rafiq S, Ali A, Imran S. Perinatal outcome in females with reduced fetal movements at term pregnancy. Neuro Quantology. 2023; 21(6): 61-5.

Ljubojević A, Gerdijan N, Pavlović R, Šebić L. Effect of Tabata training program on body fat reduction in healthy inactive women. Pedagogy of Physical Culture and Sports. 2023 May; 27(3): 198-207. doi: 10.15561/26649837.2023.0303. DOI:

Alice A, Yadav M, Verma R, Kumari M, Arora S. Effect of obesity on balance: A literature review. International Journal of Health Sciences. 2022; 6(4): 3261-79. doi: 10.53730/ijhs.v6nS4.9126. DOI:

Gries KJ, Hart CR, Kunz HE, Ryan Z, Zhang X, Parvizi M, et al. Acute responsiveness to single leg cycling in adults with obesity. Physiological Reports. 2022 Dec; 10(24): e15539. doi: 10.14814/phy2.15539. DOI:

Mohseni-Takalloo S, Beigrezaei S, Yazdanpanah Z, Rajaie SH, Soltani S, Zohrabi T, et al. Does exercise beneficially affect sex hormones when added to hypo-caloric diets in adults with overweight or obesity? A systematic review and meta-analysis of controlled clinical trials. European Journal of Endocrinology. 2022 Feb; 186(2): 285-95. doi: 10.1530/EJE-21-0675. DOI:

Al-Mosawi AJ. The preventive and predictive value of simple exercises (Stair-climbing, squat, and push-up): An educational article and expert opinion. Journal of Obesity and Fitness Management January. 2023; 1(1): 1-5. doi: 10.58489/2836-5070/004. DOI:

Adams C, Oppong P, Worlanyo JK, Agblo SP, Owusu S, Moses MO. Effects of a controlled exercise programme on anthropometric parameters, dietary habit and sleep quality of obese university students. Scientific Journal of Sport and Performance. 2022 Jul; 1(3): 136-45. doi; 10.55860/OOTH5548. DOI:

Armstrong A, Jungbluth Rodriguez K, Sabag A, Mavros Y, Parker HM, Keating SE, et al. Effect of aerobic exercise on waist circumference in adults with overweight or obesity: A systematic review and meta‐analysis. Obesity Reviews. 2022 Aug; 23(8): e13446. doi: 10.1111/obr.13446. DOI:

Singh U, Ramachandran AK, Ramirez-Campillo R, Perez-Castilla A, Afonso J, Manuel Clemente F, et al. Jump rope training effects on health-and sport-related physical fitness in young participants: A systematic review with meta-analysis. Journal of Sports Sciences. 2022 Aug; 40(16): 1801-14. doi: 10.1080/02640414.2022.2099161. DOI:

Pellegrini M, Ponzo V, Rosato R, Scumaci E, Goitre I, Benso A, et al. Changes in weight and nutritional habits in adults with obesity during the “lockdown” period caused by the COVID-19 virus emergency. Nutrients. 2020 Jul; 12(7): 2016-27. doi: 10.3390/nu12072016. DOI:

Devarshi PP, Pereyra AS, Ellis JM, Henagan TM. A single bout of cycling exercise induces nucleosome repositioning in the skeletal muscle of lean and overweight/obese individuals. Diabetes, Obesity and Metabolism. 2022 Jan; 24(1): 21-33. doi: 10.1111/dom.14541. DOI:

Batrakoulis A. Psychophysiological Adaptations to Pilates Training in Overweight and Obese Individuals: A Topical Review. Diseases. 2022 Sep; 10(4): 71-85. doi: 10.3390/diseases10040071. DOI:

Li VL, He Y, Contrepois K, Liu H, Kim JT, Wiggenhorn AL, et al. An exercise-inducible metabolite that suppresses feeding and obesity. Nature. 2022 Jun; 606(7915): 785-90. doi: 10.1038/s41586-022-04828-5. DOI:

Most J, Dervis S, Haman F, Adamo KB, Redman LM. Energy intake requirements in pregnancy. Nutrients. 2019 Aug; 11(8): 1812-29. doi: 10.3390/nu11081812. DOI:

Awobajo FO, Oyelowo OT, Okon JS. Energy demand assessment between exercising and non-exercising young female collegiate during a single exercise bout. Covenant Journal of Physical and Life Sciences. 2021 Aug; 9(1).

Alkazemi D. Gender differences in weight status, dietary habits, and health attitudes among college students in Kuwait: A cross-sectional study. Nutrition and Health. 2019 Jun; 25(2): 75-84. doi: 10.1177/0260106018817410. DOI:

Martin CK, Johnson WD, Myers CA, Apolzan JW, Earnest CP, Thomas DM, et al. Effect of different doses of supervised exercise on food intake, metabolism, and non-exercise physical activity: The E-MECHANIC randomized controlled trial. The American Journal of Clinical Nutrition. 2019 Sep; 110(3): 583-92. doi: 10.1093/ajcn/nqz054. DOI:

Ye X and Liu R. Intervention Effect of Aerobic Exercise on Physical Fitness, Emotional State and Mental Health of Drug Addicts: A Systematic Review and Meta-Analysis. International Journal of Environmental Research and Public Health. 2023 Jan; 20(3): 2272. doi: 10.3390/ijerph20032272. DOI:

Ammar A, Trabelsi K, Boukhris O, Glenn JM, Bott N, Masmoudi L, et al. Effects of aerobic-, anaerobic-and combined-based exercises on plasma oxidative stress biomarkers in healthy untrained young adults. International Journal of Environmental Research and Public Health. 2020 Apr; 17(7): 2601-12. doi: 10.3390/ijerph17072601. DOI:



DOI: 10.54393/df.v4i03.87
Published: 2023-12-31

How to Cite

Jamil, K., Baqir, S. R., Fahim, M. F., Lata, P., Khan, B., & Aziz, M. (2023). Management of Obesity through Diet and Exercise: Management of Obesity. DIET FACTOR (Journal of Nutritional and Food Sciences), 4(03), 20–28.